Dynamic Combinatorial Chemistry

7,539.00

In Drug Discovery, Bioorganic Chemistry, and Materials Science

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ISBN: 9780470096031 Category:

<b>Effective techniques for applying Dynamic Combinatorial Chemistry</b> <p>In a relatively short period, Dynamic Combinatorial Chemistry (DCC) has grown from proof-of-concept experiments in a few isolated labs to a broad conceptual framework with applications to an exceptional range of problems in molecular recognition, lead compound identification, catalyst design, nanotechnology, polymer science, and others. Bringing together a group of respected experts, this overview explains how chemists can apply DCC and fragment-based library methods to lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science.</p> <p>Chapters cover:</p> <ul> <li> <p>Basic theory</p> </li> <li> <p>Approaches to binding in proteins and nucleic acids</p> </li> <li> <p>Molecular recognition</p> </li> <li> <p>Self-sorting</p> </li> <li> <p>Catalyst discovery</p> </li> <li> <p>Materials discovery</p> </li> <li> <p>Analytical chemistry challenges</p> </li> </ul> <p>A comprehensive, single-source reference about DCC methods and applications including aspects of fragment-based drug discovery, this is a core reference that will spark the development of new solutions and strategies for chemists building structure libraries and designing compounds and materials.</p>