Enzybiotics

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Antibiotic Enzymes as Drugs and Therapeutics

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<p>Presents the latest research and applications for a new, promising approach to fighting infectious diseases</p> <p>Enzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications.</p> <p>The book begins with four chapters that review the potential applications, possible advantages, and phylogeny of enzybiotics. Next, the book explores:</p> <ul> <li> <p>A new approach to controlling infections using Gram-negative bacteria</p> </li> <li> <p>Bacteriophage holins and their membrane-disrupting activity</p> </li> <li> <p>Anti-staphylococcal lytic enzymes</p> </li> <li> <p>Membrane-targeted enzybiotics</p> </li> <li> <p>Design of phage cocktails for therapy from a host-range point of view</p> </li> <li> <p>Novel methods to identify new enzybiotics</p> </li> <li> <p>Genetically modified phages that deliver suicidal genes to target bacteria</p> </li> </ul> <p>The authors, all active enzybiotics researchers, offer a variety of perspectives, the benefit of their own hands-on investigations, as well as a thorough review and analysis of the current literature.</p> <p>As more and more bacteria become resistant to antibiotics, the development of new disease-fighting agents has become essential. This book demonstrates the full potential of the emerging field of enzybiotics to control infectious diseases. Moreover, it will serve as a springboard for new research and the development of new therapeutics.</p>