Leukemias

Edited by experts from one of the world’s largest leukemia centers, this book provides information on the biology of the variety of leukemic disorders, up-to-date diagnostic testing and many new developments in therapy. Chapters covering new treatments present an outlook for the future and explain the rationale for ongoing clinical trials. <p>Topics include:</p> <ul type=”disc”> <li>Targeted therapy, e.g. tyrosine kinase inhibitors (Flt3, Aurora kinase inhibitors, kit inhibitors, BCR-ABL inhibitors)</li> <li>Ras inhibitors</li> <li>Epigenetic therapy (hypomethylaters and histone deacetylase inhibitors)</li> <li>Lenalidomide analogs</li> <li>New chemotherapy drugs, e.g. clofarabine, cloretazine, sapacitabine, forodesine</li> <li>Combinations of chemotherapy with kinase inhibitors (e.g. ALL induction protocols in combination with dasatinib or imatinib)</li> <li>New monoclonal antibodies (lumiliximab, humaxCD20, anti-CD40)</li> <li>Thrombopoietic agents</li> </ul> <p><i>Leukemias: Principles and Practice of Therapy</i></p> <ul type=”disc”> <li>Includes practical information to guide you in challenging situations, such as treatment of elderly patients, pregnancy, relapsed and refractory disease</li> <li>Incorporates chapters on supportive care and pharmacologic information about the most frequently used drugs in this area</li> </ul>