Catalysis in Asymmetric Synthesis

Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists. <p>Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods.</p> <p>Topics covered include:</p> <ul> <li>Reduction of alkenes, ketones and imines</li> <li>Nucleophilic addition to carbonyl compounds</li> <li>Catalytic carbon-carbon bond forming reactions</li> <li>Catalytic reactions involving metal carbenoids</li> <li>Conjugate addition reactions</li> </ul> <p><i>Catalysis in Asymmetric Synthesis</i> bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist.</p>