Effects Of Genome Structure And Sequence On The Generation Of Variation And Evolution

<p>The structure of DNA varies along its sequence, which can lead to sequence-dependent variations in the fidelity of DNA copying and repair. And because the probability of distinct classes of mutations varies along a DNA sequence, variation that affects fitness will have evolutionary implications, as selection acts on heritable variation.</p> <p>This Annals volume brings together a broad interdisciplinary group of researchers to explore the impact of increasing understanding of DNA structure, repair, replication, and organization on interrelated subjects ranging from evolution, to dependence of the effect of mutagens on environmental and sequence context, to noncanonical forms of information representation in genomes.</p> <p>NOTE: <i>Annals</i> volumes are avaialble for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit <a href=”http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632″>http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632</a></p> <p>ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (<a href=”http://www.nyas.org”>www.nyas.org</a>). Members of the New York Academy of Science receive full-text access to <i>Annals</i> online and discounts on print volumes. Please visit <a href=”http://www.nyas.org/MemberCenter/Joun.aspx”>http://www.nyas.org/MemberCenter/Joun.aspx</a> for more information about becoming a member.</p>