Carbon Monoxide in Drug Discovery

<p><b>An insightful reference for the latest physiological and therapeutic studies of carbon monoxide&nbsp;</b></p> <p>In&nbsp;<i>Carbon Monoxide in Drug Discovery: Basics, Pharmacology, and Therapeutic Potential</i>, a team of distinguished&nbsp;authors delivers&nbsp;foundational knowledge, the latest research, and remaining challenges regarding the physiological roles and therapeutic efficacy of carbon monoxide&nbsp;(CO). The editors have included a broad selection of resources from leading experts in the field that discuss&nbsp;the background and physiological roles of CO, a variety of delivery forms&nbsp;including CO prodrugs using benign carriers, CO sensing, therapeutic applications, and clinical trials.&nbsp;&nbsp;</p> <p>Organized by&nbsp;topic to allow each chapter to be read individually, the book covers a wide range of topics, from&nbsp;physiological and&nbsp;patho-physiological mechanisms&nbsp;at the molecular level&nbsp;to clinical&nbsp;applications for multiple disease processes.&nbsp;</p> <p>The editors of&nbsp;<i>Carbon Monoxide in Drug Discovery</i>&nbsp;have created a compelling argument for&nbsp;shifting the accepted understanding of CO from poison to bioactive molecule with enormous clinical benefits.&nbsp;Readers will also benefit from:&nbsp;</p> <ul> <li>A thorough introduction to&nbsp;the background and physiological actions of carbon monoxide, including endogenous CO production in sickness and in health&nbsp;</li> <li>Comprehensive explorations of CO delivery forms, including&nbsp;non-carrier formulations, metal-carbonyl complexes,&nbsp;and organic CO donors&nbsp;&nbsp;</li> <li>Practical discussions of carbon monoxide sensing and scavenging, including fluorescent probes for intracellular carbon monoxide detection&nbsp;</li> <li>In-depth examinations of the therapeutic applications of CO, including CO in solid organ&nbsp;transplantation&nbsp;</li> </ul> <p>Perfect for&nbsp;professors, graduate students, and postdocs in the fields of biology, pharmacology, immunology, medicinal chemistry,&nbsp;toxicology,&nbsp;and drug delivery,&nbsp;<i>Carbon Monoxide in Drug Discovery: Basics, Pharmacology, and Therapeutic Potential</i>&nbsp;is also an invaluable resource for industrial scientists in these areas.&nbsp;</p>