Chiral Separation Methods for Pharmaceutical and Biotechnological Products

<b>Discusses chiral separations and offers guidance for selecting the optimum method for desired results</b> <p>Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development.</p> <p>Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book:</p> <ul> <li> <p>Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis</p> </li> <li> <p>Deals with the impact of chirality on the biological activity of small and large molecules</p> </li> <li> <p>Provides detailed information on useful chiral stationary phases (CSPs) for HPLC</p> </li> <li> <p>Includes handy information on selection of an appropriate CSP, including mechanistic studies</p> </li> <li> <p>Offers strategies for fast method development with HPLC, SFC, and CE</p> </li> <li> <p>Discusses preparatory methods utilized in the pharmaceutical industry</p> </li> </ul> <p>With in-depth discussions of the current state of the field as well as suggestions to assist future developments, <i>Chiral Separation Methods for Pharmaceutical and Biotechnological Products</i> is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.</p>