Drug Discovery and Development, Volume 2

<b>From first principles to real-world applications-here is the first comprehensive guide to drug discovery and development</b> <p>Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines-from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, until now, there were no authoritative references offering a complete, fully integrated picture of the process.</p> <p>The only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and develop-?ment-from initial conceptualization to commercialization to clinicians and medical practitioners.</p> <p><b>Volume 1: Drug Discovery</b> describes all the steps in the discovery process, including conceptualizing a drug, creating a library of candidates for testing, screening candidates for in vitro and in vivo activity, conducting and analyzing the results of clinical trials, and modifying a drug as necessary.</p> <p><b>Volume 2: Drug Development</b> delves into the nitty-gritty details of optimizing the synthetic route, drug manufacturing, outsourcing, and marketing-including drug coloring and delivery methods.</p> <p>Featuring contributions from a world-class team of experts, <i>Drug Discovery and Development</i>:</p> <ul> <li>Features fascinating case studies, including the discovery and development of erythromycin analogs, Tagamet, and Ultiva (remifentanil)</li> <li>Discusses the discovery of medications for bacterial infections, Parkinson’s disease, psoriasis, peptic ulcers, atopic dermatitis, asthma, and cancer</li> <li>Includes chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics</li> </ul> <p><i>Drug Discovery and Development</i> is an indispensable working resource for industrial chemists, biologists, biochemists, and executives who work in the pharmaceutical industry.</p>