Pheochromocytoma

Pheochromocytoma is a rare neuroendocrine tumor with a highly variable presentation. There is lack of agreement about the most efficient and cost-effective methods for diagnosis and localization of the tumor, which can be lethal if not identified and treated promptly.Autopsy studies indicate that up to 50% of all cases remain undiagnosed until death. <br /> <p>Between 30 and 35% of the tumors have a hereditary basis. Development of malignancy is highly variable — from less than 5% to more than 50% depending on the mutation; there is currently no effective cure.<br /> </p> <p>This volume encompasses a number of themes in several sections: genetics and clinical decision-making; genetics, molecular pathways of tumorigenesis, and divergent phenotypes; kaleidoscopic presentations and a minefield for differential diagnosis of pheochromocytoma; biochemical diagnosis: can we reach consensus?; tumor localization and the evolving importance of functional imaging; and new molecular markers and targets for diagnosis and treatment of malignant pheochromcytoma.<br /> </p> <p><b>NOTE:</b> Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit <a href=”http://www.blackwellpublishing.com/nyas”>www.blackwellpublishing.com/nyas</a>.</p> <p><b>ACADEMY MEMBERS</b>: Please contact the New York Academy of Sciences directly to place your order (<a href=”http://www.nyas.org/”>www.nyas.org</a>). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit <a href=”http://www.nyas.org/MemberCenter/Join.aspx”>http://www.nyas.org/MemberCenter/Join.aspx</a> for more information about becoming a member</p>