Pitfalls and Errors of HPLC in Pictures

The third edition of this popular problem-solving guide for this widely-used method includes eleven completely new examples and<br> several updated ones, adding up to 100 contributions about pitfalls and errors in HPLC. Each example is presented on a double page with the<br> text on the left-hand and a fi gure on the right-hand side, true to the motto ‘a picture says more than a thousand words’. In addition, the<br> author presents essential fundamentals as well as helpful strategies, such as equipment tests or quality assurance processes. <br> <br> New in this edition<br> <br> * Variability of the standard deviation<br> * Infl uence of the acid type and concentration in the eluent<br> * Water as an unintentional additive in the mobile phase<br> * Inadequate purity of mobile phase water<br> * Incomplete degassing<br> * Inadequate stabilization of the extraction solvent<br> * Tailing of phosphate compounds in the presence of steel<br> * Different detection properties of diastereomers<br> * Detector overload in ELSD<br> * System suitability test<br> * From repeatability to reproducibility<br> <br> A must-have resource for all users – showing how to use HPLC efficiently and obtain reliable results.