Sodium Channels and Neuronal Hyperexcitability

Recent progress has led to a better understanding of the molecular structure of sodium channels, how they work and the mechanisms that restrict their expression to particular cell types. <p>This book explains how these channels are modulated in various pathological states to enable the development of therapeutic strategies based on sodium channel restoration.</p> <p>The authors present the most current research on sodium channels and neuronal function.</p> <ul> <li>Brings together both the basic biology and biophysics with detailed consideration of the medical applications in chronic pain and epilepsy.</li> <li>Includes coverage of channelopathies, sodium channel gene expression, the modulation of sodium channels, and molecular mechanisms of gating and drug block of sodium channels.</li> </ul>